HOT MELT EXTRUSION SYSTEM
For pharmaceutical application
Hot Melt Extrusion[HME] has emerged as a novel processing technology in developing molecular dispersions of Active Pharmaceutical Ingredients[APIs] into various polymer and lipid matrices. Currently, this technology is extensively used in pharmaceutical research and development for solubility enhancement, time controlled, modified, extended and targeted drug delivery.
STEER H.M.E.S is a complete system with its core unit ‘Hot Melt Extruder’ having the STEER EPZ products like screw elements & barrels. Appropriate with both up-stream and down-stream components like micro feeder, split and side feeder, refill silo and its associated platform, chill roll unit, chill air conveyor unit, pelletizer and flaker complete the system. The system is modular, comprehensive and scalable.
Pharmaceutical Compounding using Hot Melt Extrusion(HME) involves achieving a homogenous solid dispersion or solution by mixing and/or melting API with one or more excipients such as polymers, lipids, surfactants, diluents, lubricants, glidants, plasticizers and other modifiers for the purpose of stabilization, bioavailability enhancement, controlled release or taste masking and improved delivery especially in oral and trans-dermal systems.
STEER HMES OMICRON 10 [MINI] offers the best platform for Universities and Pharmaceutical Companies doing hard core research on hot melt extrusion on NCE and/or applications requiring high potent API. OMICRON 10 is designed to handle very low volumes. The option of changing process section with four different Do/Di (1.27,1.42,1.55,1.71) ratios to vary the shear rate makes OMICRON 10 the best extruder platform for pharmaceutical research.
STEER HMES OMICRON 12 is an excellent extruder for conducing feasibility/proof of concept studies in pharmaceutical research. With micro feeder and combinational downstream ancillaries, OMICRON 12 is a complete solution for scale up studies for the drug development. OMICRON 12 is well-known to process most of the excipients used in pharma research.
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STEER H.M.E.S OMega 20
FOR PILOT PRODUCTION
STEER HMES OMEGA 20 is the most suitable pilot scale extruder for Scale-up studies, Exhibit/Clinical batches. OMEGA 20 is designed to comply with GMP requirement of automation, contact surface and cleaning.
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DOWNLOAD BROCHURE
EPZ PHARMA BROCHURE
STEER H.M.E.S OMega 30
FOR COMMERCIAL LARGE SCALE
STEER H.M.E.S OMega 40
FOR COMMERCIAL LARGE SCALE
STEER’s OMEGA PHARMA twin-screw extruder created for pharmaceutical applications is modular in design. The HOT MELT EXTRUSION SYSTEM consists of co-rotating fully wiping twin-screws and clamshell barrel. The key tasks of the extruder are mixing, homogenizing and degassing. Its modular design offers a choice of screw elements which allow altering the configuration of the intake, mixing and metering zones with respect to different applications. Flexibility, continuous operation process capability and higher energy efficiency make the OMEGA PHARMA HOT EXTRUSION SYSTEM the ideal Pharma extruder.
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О компании STEER
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