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Hot Melt Extrusion (HME) is a proven technology in developing molecular dispersions of Active Pharmaceutical Ingredients (APIs) into polymer and lipid matrices. The technology involves achieving a homogenous solid dispersion or solution by mixing and/or melting API with one or more excipients such as polymers, lipids, surfactants, diluents, lubricants, glidants, plasticizers and other modifiers for the purpose of stabilization, bioavailability enhancement, controlled release or taste masking and improved delivery especially in oral and trans-dermal systems.
Easy cleaning and maintenance
Precise control of process parameters
Assured melt quality
Better mixing capability
Shorter residence time
Continuous process
Processing of temperature sensitive actives
STEER patented elements for pharmaceutical materials
24x7 service and spares support
Integration with PAT tools
Audit trails